ICD-10 Code A52.10 – Symptomatic neurosyphilis, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Symptomatic neurosyphilis, unspecified is A52.10.
2026 ICD-10-CM Diagnosis Code A52.10 – Symptomatic neurosyphilis, unspecified

What it is

A52.10 identifies symptomatic neurosyphilis when the specific neurologic syndrome is not further specified. Use it for documented neurosyphilis with clinical symptoms involving the central nervous system.

Clinical signs

Clinical features vary; refer to documentation. Common findings may include neurologic deficits, cognitive changes, sensory abnormalities, or meningitis-like symptoms consistent with neurosyphilis.

When to use this code

Use this code when the record clearly states symptomatic neurosyphilis but does not name a more specific form. It fits cases where neurologic involvement is documented and the provider has not specified tabes dorsalis, general paresis, or another subtype.

If the chart only notes syphilis without neurologic symptoms, this code is not appropriate. Check documentation for the exact manifestation and whether a different neurosyphilis code is supported.

Do not use for

Do not use it for asymptomatic neurosyphilis or for syphilis without nervous system involvement. Do not assign it when the provider documents a more specific neurosyphilis diagnosis.

Coding tip

Verify that the note supports symptomatic neurologic disease and that no more specific subtype is documented before selecting A52.10.

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