ICD-10 Code C46.1 – Kaposi’s sarcoma of soft tissue (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Kaposi’s sarcoma of soft tissue is C46.1.
2026 ICD-10-CM Diagnosis Code C46.1 – Kaposi’s sarcoma of soft tissue

What it is

C46.1 identifies Kaposi’s sarcoma when it involves soft tissue. It is a malignant vascular tumor that can present as a localized or more extensive lesion in soft tissue structures.

Clinical signs

Clinical features vary; refer to documentation. Typical findings include violaceous or reddish-brown nodules, plaques, or masses, with pathology confirming Kaposi’s sarcoma.

When to use this code

Use C46.1 when the record clearly states Kaposi’s sarcoma of soft tissue. Code it when the provider documents soft tissue involvement rather than skin, lymph nodes, or another specific site. If the site is unclear, check documentation before assigning the code.

Do not use for

Do not use this code for Kaposi’s sarcoma limited to skin, lymph nodes, or other named sites. Do not assign it when the chart only says “Kaposi’s sarcoma” without soft tissue involvement.

Coding tip

Match the documented anatomic site exactly; Kaposi’s sarcoma codes are site-specific.

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