ICD-10 Code D52.1 – Drug-induced folate deficiency anemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D52.1 – Drug-induced folate deficiency anemia
What it is
D52.1 identifies folate deficiency anemia caused by a medication or other drug exposure. Use it when the record states the anemia is drug-induced and linked to folate depletion.
Clinical signs
Clinical features vary; refer to documentation. Commonly, patients may have findings of anemia and evidence of folate deficiency, with the medication cause documented by the provider.
When to use this code
Use D52.1 when the clinician documents folate deficiency anemia as caused by a drug. This is appropriate when the chart clearly links the anemia to medication use, adverse effect, or other drug exposure.
If the cause is not stated, check documentation before assigning this code. Do not assume drug causation from anemia alone.
Do not use for
Do not use this code for folate deficiency anemia without a documented drug cause. Check documentation if the condition is due to diet, malabsorption, pregnancy, or another non-drug reason.
Coding tip
Confirm both the folate deficiency anemia and the medication-related cause in the provider note before coding D52.1.