ICD-10 Code L27 – Dermatitis due to substances taken internally (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Dermatitis due to substances taken internally is L27.
2026 ICD-10-CM Diagnosis Code L27 – Dermatitis due to substances taken internally

What it is

L27 identifies dermatitis caused by a substance taken internally, such as a medication, food, or other ingested agent. It is used when the skin reaction is attributed to internal exposure rather than direct contact.

Clinical signs

Typical findings include a rash, erythema, itching, or other inflammatory skin changes after internal exposure. Clinical features vary; refer to documentation for the specific reaction pattern and suspected trigger.

When to use this code

Use L27 when the record links dermatitis to a substance taken by mouth or otherwise absorbed internally and the clinician documents that relationship. This code fits cases where the skin reaction is the primary documented issue. Check documentation if the exact agent or reaction type is unclear.

Do not use for

Do not use this code for dermatitis caused by direct skin contact with an external substance. Also avoid it when the chart documents a different diagnosis or when the internal cause is not supported.

Coding tip

Assign the code only when the provider clearly documents an internal substance as the cause of the dermatitis.

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