ICD-10 Code L27.1 – Localized skin eruption due to drugs and medicaments taken internally (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code L27.1 – Localized skin eruption due to drugs and medicaments taken internally
What it is
L27.1 identifies a localized skin eruption caused by a drug or medicament taken internally. Use it when the reaction is limited to a specific area rather than widespread.
Clinical signs
Findings usually include a localized rash, erythema, or other skin irritation after internal medication exposure. Clinical features vary; refer to documentation.
When to use this code
Use this code when the provider documents a localized cutaneous drug reaction linked to an oral, injected, or otherwise internal medication. It fits cases where the eruption is described as limited in distribution and not generalized. Check documentation for the specific drug and reaction type.
Do not use for
Do not use L27.1 for generalized drug eruptions, contact dermatitis, or skin reactions from external exposure. If the record does not clearly link the eruption to an internal medication, check documentation.
Coding tip
Confirm both the medication exposure and the localized nature of the rash before assigning L27.1.