ICD-10 Code I25.750 – Atherosclerosis of native coronary artery of transplanted heart with unstable angina (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I25.750 – Atherosclerosis of native coronary artery of transplanted heart with unstable angina
What it is
This code identifies atherosclerotic narrowing in the native coronary arteries of a transplanted heart when unstable angina is present. It reflects ischemic chest pain related to coronary artery disease in the transplanted heart.
Clinical signs
Clinical features may include chest discomfort, pressure, or other ischemic symptoms that are new, worsening, or occurring at rest. Clinical features vary; refer to documentation.
When to use this code
Use this code when the provider documents a transplanted heart with native coronary artery atherosclerosis and unstable angina. It is appropriate when the record clearly links the angina to the coronary disease in the transplanted heart. Check documentation if the note does not specify unstable angina or the transplant context.
Do not use for
Do not use it for stable angina, unspecified chest pain, or coronary disease without documentation of a transplanted heart. Do not assign it if the record does not confirm unstable angina.
Coding tip
Verify both the transplant status and the unstable angina diagnosis in the provider note before assigning I25.750.