ICD-10 Code I25.110 – Atherosclerotic heart disease of native coronary artery with unstable angina pectoris (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I25.110 – Atherosclerotic heart disease of native coronary artery with unstable angina pectoris
What it is
This code identifies coronary artery disease in a native coronary artery with unstable angina pectoris. It indicates ischemic chest pain related to atherosclerosis, without stating an acute myocardial infarction.
Clinical signs
Typical documentation includes chest pain or pressure that is new, worsening, or occurring at rest, with clinical concern for unstable angina. Clinical features vary; refer to documentation.
When to use this code
Use I25.110 when the provider documents atherosclerotic heart disease of a native coronary artery and specifically identifies unstable angina pectoris. It is appropriate when the record links the angina to coronary atherosclerosis. Check documentation if the note only says chest pain or coronary artery disease without instability.
Do not use for
Do not use this code for stable angina, acute myocardial infarction, or angina without documented coronary atherosclerosis. If the vessel type is not native or the diagnosis is not confirmed, check documentation.
Coding tip
Confirm both elements in the note: native coronary atherosclerosis and unstable angina; both must be documented for accurate code selection.