ICD-10 Code I25.1 – Atherosclerotic heart disease of native coronary artery (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I25.1 – Atherosclerotic heart disease of native coronary artery
What it is
This code identifies coronary artery disease caused by atherosclerosis in the patient’s own coronary arteries. It is used when plaque buildup narrows or hardens the vessels that supply the heart muscle.
Clinical signs
Clinical features vary; refer to documentation. Common findings include angina, exertional chest discomfort, ischemic ECG changes, or evidence of coronary narrowing on imaging or angiography.
When to use this code
Use I25.1 when the record clearly documents atherosclerotic disease of a native coronary artery, with or without stable ischemic symptoms. It also fits when coronary artery disease is confirmed and the provider specifies native vessel involvement. If the note only says “CAD” or “coronary atherosclerosis,” check documentation for specificity.
Do not use for
Do not use this code for coronary disease involving bypass grafts, transplanted hearts, or acute myocardial infarction. If the diagnosis is only suspected or undocumented, check documentation.
Coding tip
Code the documented coronary anatomy carefully, and add any applicable associated conditions only when the provider confirms them.