ICD-10 Code I25.721 – Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I25.721 – Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm
What it is
This code identifies atherosclerotic narrowing in an autologous coronary bypass graft, with angina and documented spasm. Use it when the graft itself is the diseased vessel and the record confirms spasm.
Clinical signs
Typical findings include chest pain or pressure consistent with angina in a patient with prior coronary artery bypass grafting. Documentation should also show graft atherosclerosis and a confirmed spasm; clinical features vary, refer to documentation.
When to use this code
Use this code when the provider documents coronary artery disease affecting an autologous graft, along with angina pectoris and documented spasm. It applies to postoperative bypass graft disease, not native coronary artery disease.
Choose it when the note clearly ties symptoms and imaging, catheterization, or other assessment to the bypass graft. If the record does not specify the graft type or spasm, check documentation before assigning the code.
Do not use for
Do not use this code for angina without documented graft atherosclerosis or spasm. Do not use it for native coronary artery disease, other bypass graft types, or unspecified chest pain.
Coding tip
Verify three elements in the note: autologous graft, angina pectoris, and documented spasm.