ICD-10 Code I22.2 – Subsequent non-ST elevation (NSTEMI) myocardial infarction (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Subsequent non-ST elevation (NSTEMI) myocardial infarction is I22.2.
2026 ICD-10-CM Diagnosis Code I22.2 – Subsequent non-ST elevation (NSTEMI) myocardial infarction

What it is

This code identifies a new NSTEMI that occurs after a recent myocardial infarction. It means the patient has another heart attack during the acute period, and it is not the initial event.

Clinical signs

Typical findings include ischemic chest pain or equivalent symptoms, ECG changes without ST elevation, and evidence of ongoing myocardial injury. Clinical features vary; refer to documentation.

When to use this code

Use I22.2 when the record clearly documents a subsequent NSTEMI occurring within the acute phase of a prior MI. You should confirm that the provider identifies it as a new infarction, not persistent injury from the earlier event.

Apply the code when the chart distinguishes the later NSTEMI from the original myocardial infarction. Check documentation if the timing or relationship to the prior MI is unclear.

Do not use for

Do not use this code for the initial NSTEMI or for old, healed myocardial infarction. Do not assign it when documentation only describes chest pain, unstable angina, or nonspecific troponin elevation.

Coding tip

Verify that the provider documents a subsequent infarction after a recent MI before assigning I22.2.

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