ICD-10 Code F19.981 – Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction is F19.981.
2026 ICD-10-CM Diagnosis Code F19.981 – Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction

What it is

This code identifies sexual dysfunction caused by use of another psychoactive substance that is not otherwise specified. Use it when the record links the sexual problem directly to substance use.

Clinical signs

Clinical features vary; refer to documentation. The chart should show sexual dysfunction and a clinician’s attribution to psychoactive substance use, such as impaired desire, arousal, or performance.

When to use this code

Use this code when the provider documents unspecified psychoactive substance use with a substance-induced sexual dysfunction. It fits cases where the substance is not named more specifically or is recorded as “other” or “unspecified.”

Code from the provider’s diagnosis, not from suspicion alone. If the record does not clearly connect the dysfunction to substance use, check documentation before assigning F19.981.

Do not use for

Do not use this code for sexual dysfunction without a documented substance cause. Also avoid it when a more specific substance-related diagnosis is documented.

Coding tip

Confirm both elements in the note: unspecified psychoactive substance use and the substance-induced sexual dysfunction link.

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