ICD-10 Code F19.288 – Other psychoactive substance dependence with other psychoactive substance-induced disorder (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance dependence with other psychoactive substance-induced disorder is F19.288.
2026 ICD-10-CM Diagnosis Code F19.288 – Other psychoactive substance dependence with other psychoactive substance-induced disorder

What it is

This code identifies dependence on another psychoactive substance, along with a separate disorder caused by that substance. Use it when the record shows both dependence and a substance-induced mental or physical condition.

Clinical signs

Clinical features vary; refer to documentation. You may see evidence of compulsive use, tolerance, withdrawal, or continued use despite harm, plus symptoms attributed to the substance-induced disorder.

When to use this code

Use this code when the provider documents dependence on a psychoactive substance not named elsewhere and also documents an induced disorder linked to that substance. It supports cases where the induced condition is part of the diagnosis, not just substance use alone.

Code only when both elements are clearly stated in the chart. Check documentation if the record names the substance, but the induced disorder is unspecified or not confirmed.

Do not use for

Do not use this code for simple use, abuse, or intoxication without dependence. Do not use it when the induced disorder is absent or when another more specific substance-related code is documented.

Coding tip

Verify that the note supports both dependence and a substance-induced disorder before assigning F19.288.

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