ICD-10 Code F19.2 – Other psychoactive substance dependence (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance dependence is F19.2.
2026 ICD-10-CM Diagnosis Code F19.2 – Other psychoactive substance dependence

What it is

F19.2 identifies dependence on a psychoactive substance not specifically named in another drug category. It means the patient has a pattern of continued use with dependence features, and you should code the specific substance when documented.

Clinical signs

Clinical features vary; refer to documentation. Common dependence indicators include strong craving, impaired control over use, tolerance, withdrawal, and continued use despite harm.

When to use this code

Use this code when the record clearly documents dependence on an other or unspecified psychoactive substance and no more specific ICD-10-CM code is available. It may apply when the substance is named in the chart but not separately classified in the code set. If the substance is known, verify whether a more specific code exists before assigning F19.2.

Do not use for

Do not use this code for simple use, abuse, intoxication, or withdrawal without dependence. Do not use it when a specific substance dependence code is documented and available.

Coding tip

Check the substance name carefully and code the most specific dependence diagnosis supported by documentation.

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