ICD-10 Code F19.181 – Other psychoactive substance abuse with psychoactive substance-induced sexual dysfunction (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance abuse with psychoactive substance-induced sexual dysfunction is F19.181.
2026 ICD-10-CM Diagnosis Code F19.181 – Other psychoactive substance abuse with psychoactive substance-induced sexual dysfunction

What it is

This code identifies abuse of another psychoactive substance when it causes a sexual dysfunction directly linked to the substance. Use it when documentation ties the sexual problem to the substance use disorder.

Clinical signs

Clinical features vary; refer to documentation. Records may note reduced sexual desire, arousal, or performance problems occurring during or after substance use, with the clinician attributing the dysfunction to the psychoactive substance.

When to use this code

Use this code when the provider documents both abuse of a non-specified psychoactive substance and a substance-induced sexual dysfunction. It fits situations where the sexual symptoms are not better explained by another medical, psychiatric, or medication cause. Check documentation if the substance is named, but the chart still places it under “other psychoactive substance.”

Do not use for

Do not use this code for sexual dysfunction unrelated to substance use, or when the record only shows substance abuse without sexual symptoms. If the substance is known and a more specific code applies, code that instead.

Coding tip

Confirm that the provider links the sexual dysfunction to the substance abuse before assigning F19.181.

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