ICD-10 Code F11.121 – Opioid Abuse with Intoxication Delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F11.121 – Opioid abuse with intoxication delirium
What it is
This code identifies opioid abuse complicated by delirium caused by intoxication. Use it when the record shows harmful opioid use and an acute confusional state linked to opioid effects.
Clinical signs
Typical findings include disturbed attention, disorientation, and an altered level of awareness during opioid intoxication. Clinical features vary; refer to documentation for the delirium diagnosis and its relationship to opioid use.
When to use this code
Use this code when the clinician documents opioid abuse and states that delirium is due to intoxication. It is appropriate when the delirium is acute and tied to the opioid-related episode, not another cause. Check documentation if the substance relationship is unclear.
Do not use for
Do not use this code for opioid dependence without abuse, or for delirium from withdrawal, infection, or another medical condition. If the chart does not support intoxication-related delirium, check documentation.
Coding tip
Confirm both the opioid abuse and the intoxication delirium are documented before assigning F11.121.