ICD-10 Code E74.31 – Sucrase-isomaltase deficiency (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sucrase-isomaltase deficiency is E74.31.
2026 ICD-10-CM Diagnosis Code E74.31 – Sucrase-isomaltase deficiency

What it is

E74.31 identifies sucrase-isomaltase deficiency, a disorder where the intestine cannot properly break down sucrose and some starches. This leads to poor digestion after eating certain carbohydrates.

Clinical signs

Common features include bloating, abdominal pain, gas, and diarrhea after sucrose- or starch-containing foods. Clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents sucrase-isomaltase deficiency, congenital or acquired, as the cause of carbohydrate malabsorption. It may also apply when testing or specialist assessment confirms the diagnosis. Check documentation if the record only mentions nonspecific food intolerance or chronic diarrhea.

Do not use for

Do not use it for general lactose intolerance, celiac disease, or other malabsorption disorders unless sucrase-isomaltase deficiency is specifically documented. Do not assign it from symptoms alone.

Coding tip

Code E74.31 only when the diagnosis is clearly stated; if the chart is vague, query the provider.

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