ICD-10 Code E74.1 – Disorders of fructose metabolism (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E74.1 – Disorders of fructose metabolism
What it is
E74.1 identifies inherited disorders in which the body cannot properly process fructose, a sugar found in fruit, honey, and some sweeteners. This code covers metabolic conditions such as fructose intolerance or fructose malabsorption when documented as a disorder of fructose metabolism.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include gastrointestinal symptoms after fructose exposure, poor feeding in infants, vomiting, abdominal pain, bloating, or hypoglycemia in hereditary forms.
When to use this code
Use E74.1 when the provider documents a fructose metabolism disorder, including hereditary fructose intolerance or another specified fructose-processing defect. It is appropriate when the diagnosis is confirmed or clearly stated in the record, even if the current encounter is for counseling or follow-up.
Code this when the chart links symptoms to fructose exposure and the clinician identifies a metabolic disorder. Check documentation if the note only mentions dietary intolerance without a metabolic diagnosis.
Do not use for
Do not use E74.1 for nonspecific abdominal upset, food intolerance, or irritable bowel symptoms without a documented fructose metabolism disorder. Check documentation if the condition is instead described as a different carbohydrate metabolism problem.
Coding tip
Look for the exact provider wording; “fructose intolerance” alone may not justify E74.1 unless the record states a metabolic disorder.