ICD-10 Code E16.8 – Other specified disorders of pancreatic internal secretion (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E16.8 – Other specified disorders of pancreatic internal secretion
What it is
E16.8 is used for pancreatic hormone or internal secretion disorders that do not fit a more specific ICD-10 category. It covers documented conditions affecting pancreatic endocrine function when the record identifies a distinct disorder but not a named code.
Clinical signs
Clinical features vary; refer to documentation. You may see signs of abnormal pancreatic hormone activity, such as unexplained glucose instability or other endocrine dysfunction noted by the clinician.
When to use this code
Use E16.8 when the provider documents a specific disorder of pancreatic internal secretion and no more precise code is available. This may apply when the diagnosis is confirmed but the exact subtype is not stated in the record. Check documentation if the note only describes a symptom or suspected condition.
Do not use for
Do not use this code for diabetes mellitus, hypoglycemia without a specified pancreatic endocrine disorder, or nonspecific abdominal pancreatic disease. If the record supports a different endocrine or pancreatic diagnosis, code that condition instead.
Coding tip
Code E16.8 only when the provider clearly documents an unspecified or other specified pancreatic endocrine disorder.