ICD-10 Code C92.21 – Atypical chronic myeloid leukemia, BCR/ABL-negative, in remission (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.21 – Atypical chronic myeloid leukemia, BCR/ABL-negative, in remission
What it is
This code identifies atypical chronic myeloid leukemia that is BCR/ABL-negative and currently documented as in remission. Use it when the diagnosis is established and the provider states the disease is not active.
Clinical signs
Clinical features vary; refer to documentation. This leukemia is generally recognized by a prior confirmed diagnosis, BCR/ABL negativity, and a remission status noted by the treating clinician.
When to use this code
Use C92.21 when the record clearly states atypical chronic myeloid leukemia, BCR/ABL-negative, and remission. It is appropriate for follow-up encounters or ongoing monitoring when the condition remains in remission. If the chart does not specify remission, check documentation before coding.
Do not use for
Do not use this code for chronic myeloid leukemia with BCR/ABL positivity or when remission is not documented. If the leukemia type is unclear, check documentation.
Coding tip
Match the exact leukemia subtype and remission status in the provider note before assigning C92.21.