ICD-10 Code C92.12 – Chronic myeloid leukemia, BCR/ABL-positive, in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.12 – Chronic myeloid leukemia, BCR/ABL-positive, in relapse
What it is
This code identifies chronic myeloid leukemia that is BCR/ABL-positive and has returned after remission or prior control. Use it when the record clearly states relapse.
Clinical signs
Clinical features vary; refer to documentation. Records may describe recurrent leukemia, rising disease burden, or return of prior CML findings after a period of response.
When to use this code
Use C92.12 when the provider documents chronic myeloid leukemia, BCR/ABL-positive, and specifies relapse. It fits follow-up visits where the condition has recurred after remission or treatment response. Do not infer relapse from history alone; the note should say it.
Do not use for
Do not use this code for newly diagnosed CML, remission status, or unspecified chronic myeloid leukemia. If the documentation does not confirm relapse, check documentation before coding.
Coding tip
Look for the exact words “relapse,” “recurrent,” or equivalent provider wording before assigning C92.12.