ICD-10 Code C88.8 – Other malignant immunoproliferative diseases (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C88.8 – Other malignant immunoproliferative diseases
What it is
C88.8 identifies malignant immunoproliferative disorders that do not fit a more specific ICD-10 category. Use it for documented malignant immune-cell or plasma-cell proliferative disease when the exact subtype is not stated.
Clinical signs
Clinical features vary; refer to documentation. These disorders may present with abnormal lymphoid or plasma-cell proliferation, organ involvement, or findings consistent with a malignant hematologic process.
When to use this code
Use C88.8 when the provider documents an other specified malignant immunoproliferative disease and no more specific code applies. It is also appropriate when the record confirms a malignant immunoproliferative disorder but does not identify a precise subtype. Check documentation if the diagnosis is unclear.
Do not use for
Do not use this code for benign or reactive lymphoid conditions, or for a more specific malignant hematologic diagnosis that is documented elsewhere. If the condition is unspecified or unconfirmed, check documentation.
Coding tip
Code the most specific documented malignancy first, and use C88.8 only when the record supports “other” malignant immunoproliferative disease.