ICD-10 Code C81.42 – Lymphocyte-rich Hodgkin lymphoma, intrathoracic lymph nodes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.42 – Lymphocyte-rich Hodgkin lymphoma, intrathoracic lymph nodes
What it is
This code identifies lymphocyte-rich Hodgkin lymphoma involving intrathoracic lymph nodes, such as mediastinal or hilar nodes. Use it when the record specifies this Hodgkin lymphoma subtype and the thoracic nodal site.
Clinical signs
Clinical features vary; refer to documentation. Common findings in Hodgkin lymphoma include enlarged lymph nodes, especially in the chest, and may include systemic “B” symptoms or imaging evidence of intrathoracic nodal disease.
When to use this code
Use C81.42 when the provider documents lymphocyte-rich Hodgkin lymphoma and clearly identifies intrathoracic lymph nodes as the involved site. It is also appropriate when pathology, oncology notes, or discharge summaries confirm this exact diagnosis. If the site or subtype is not stated, check documentation before assigning the code.
Do not use for
Do not use this code for other Hodgkin lymphoma subtypes, unspecified Hodgkin lymphoma, or lymphoma confined to non-thoracic nodes. If the record only says “lymphoma” or the anatomic site is unclear, check documentation.
Coding tip
Match both the histology and the nodal location exactly; if either element is missing, query the record before coding.