ICD-10 Code C81.2 – Mixed cellularity Hodgkin lymphoma (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.2 – Mixed cellularity Hodgkin lymphoma
What it is
C81.2 identifies mixed cellularity Hodgkin lymphoma, a subtype of Hodgkin lymphoma. Use it when documentation names this specific histology rather than another Hodgkin lymphoma type.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include lymph node enlargement and other lymphoma-related systemic features, but the record should confirm the mixed cellularity subtype.
When to use this code
Use C81.2 when the provider documents mixed cellularity Hodgkin lymphoma, whether newly diagnosed or under active evaluation. It also applies when pathology, oncology notes, or discharge summaries clearly identify this subtype. If the subtype is not stated, check documentation before assigning this code.
Do not use for
Do not use this code for other Hodgkin lymphoma subtypes, unspecified Hodgkin lymphoma, or non-Hodgkin lymphoma. If the record only says “lymphoma” or is unclear, check documentation.
Coding tip
Code the documented subtype exactly; mixed cellularity should not be inferred from general lymphoma wording.