ICD-10 Code C49.6 – Malignant neoplasm of connective and soft tissue of trunk, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C49.6 – Malignant neoplasm of connective and soft tissue of trunk, unspecified
What it is
This code identifies a malignant tumor arising from connective or soft tissues in the trunk when the exact site is not documented. Use it for cancers involving structures such as muscle, fat, fibrous tissue, or related soft tissues.
Clinical signs
Clinical features vary; refer to documentation. Commonly, these tumors present as a growing mass, localized swelling, pain, or functional limitation, but the record must support the diagnosis and trunk location.
When to use this code
Use C49.6 when the provider documents a primary malignant neoplasm of connective or soft tissue in the trunk and does not specify a more exact anatomic site. It may also apply when the record confirms malignancy but the location within the trunk remains unspecified. Check documentation if the tumor is described only by histology or if another site is named.
Do not use for
Do not use this code for benign soft tissue tumors, metastatic disease to the trunk, or malignancies with a clearly documented more specific trunk site. If the chart names a different primary site, code that site instead.
Coding tip
Code the most specific trunk site available; if the note only says “trunk” or “soft tissue of trunk,” C49.6 is the correct unspecified option.