ICD-10 Code A51.49 – Other secondary syphilitic conditions (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other secondary syphilitic conditions is A51.49.
2026 ICD-10-CM Diagnosis Code A51.49 – Other secondary syphilitic conditions

What it is

A51.49 identifies secondary syphilis manifestations that do not fit a more specific secondary syphilis code. Use it when the record confirms secondary syphilis, but the exact presentation is otherwise described or unspecified.

Clinical signs

Secondary syphilis commonly presents with a generalized rash, mucous membrane lesions, lymphadenopathy, or patchy hair loss. Clinical features vary; refer to documentation.

When to use this code

Use this code when the clinician documents secondary syphilis and the chart does not support a more specific secondary syphilis code. It may apply to atypical or mixed secondary findings that are still clearly secondary syphilitic. Check documentation if the stage is uncertain.

Do not use for

Do not use it for primary, latent, tertiary, or congenital syphilis. If the note identifies a specific secondary manifestation with its own code, code that condition instead.

Coding tip

Confirm the stage and any named lesion in the assessment before assigning A51.49.

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