ICD-10 Code J45.21 – Mild intermittent asthma with (acute) exacerbation (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Mild intermittent asthma with (acute) exacerbation is J45.21.
2026 ICD-10-CM Diagnosis Code J45.21 – Mild intermittent asthma with (acute) exacerbation

What it is

J45.21 identifies mild intermittent asthma that has worsened into an acute flare. Use it when the record supports both the asthma severity pattern and a current exacerbation.

Clinical signs

Typical findings include wheezing, cough, chest tightness, and shortness of breath during an asthma flare. Clinical features vary; refer to documentation for the severity pattern and whether the episode is acute.

When to use this code

Use this code when the clinician documents mild intermittent asthma and notes an acute exacerbation, attack, or flare. It also fits encounters for worsening asthma symptoms requiring evaluation, as long as the severity classification is stated. If the chart does not specify mild intermittent asthma, check documentation.

Do not use for

Do not use this code for asthma without an exacerbation, or when a different asthma severity is documented. If the record only says asthma or the severity is unclear, check documentation.

Coding tip

Code both the asthma type and the acute exacerbation only when the provider clearly documents both elements.

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