ICD-10 Code G92.02 – Immune effector cell-associated neurotoxicity syndrome, grade 2 (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code G92.02 – Immune effector cell-associated neurotoxicity syndrome, grade 2
What it is
Use this code for immune effector cell therapy-related neurotoxicity at grade 2 severity. It identifies a moderate neurologic adverse effect linked to immune effector cell treatment, not a primary neurologic disorder.
Clinical signs
Clinical features vary; refer to documentation. Grade 2 generally indicates a moderate neurologic change that is more than mild and requires clinical attention, with findings described in the treating team’s assessment.
When to use this code
Assign G92.02 when the record clearly documents immune effector cell-associated neurotoxicity syndrome, grade 2. Use it for post-therapy neurologic toxicity after immune effector cell treatment when the provider specifies this grade. If the grade is not stated, check documentation before coding.
Do not use for
Do not use this code for neurologic symptoms without a documented immune effector cell association or without grade 2 severity. Do not substitute it for other encephalopathy, seizure, or delirium diagnoses unless the provider links them specifically.
Coding tip
Code the exact toxicity grade documented by the provider; if the grade is missing, query for clarification rather than assuming G92.02.