ICD-10 Code F19.16 – Other psychoactive substance abuse with psychoactive substance-induced persisting amnestic disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.16 – Other psychoactive substance abuse with psychoactive substance-induced persisting amnestic disorder
What it is
This code identifies abuse of another psychoactive substance with a lasting amnestic disorder caused by that substance. Use it when the memory problem is documented as persisting and directly linked to the substance.
Clinical signs
Typical findings include impaired recent memory, difficulty learning new information, and gaps in recall after substance use. Clinical features vary; refer to documentation for the specific substance and duration of the amnestic disorder.
When to use this code
Use F19.16 when the record clearly states psychoactive substance abuse and a persisting amnestic disorder due to that substance. The documentation should support both the substance category and the ongoing memory impairment.
Choose this code when the clinician identifies the amnestic disorder as substance-induced rather than due to another neurologic or psychiatric cause. Check documentation if the substance is unspecified or the persistence of symptoms is unclear.
Do not use for
Do not use this code for simple intoxication, withdrawal, or short-term memory loss without a persisting amnestic disorder. Do not use it if the amnesia is better explained by another condition.
Coding tip
Verify that both abuse and the persisting amnestic disorder are documented before assigning F19.16.