ICD-10 Code F16.280 – Hallucinogen dependence with hallucinogen-induced anxiety disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F16.280 – Hallucinogen dependence with hallucinogen-induced anxiety disorder
What it is
This code identifies a pattern of hallucinogen dependence with anxiety symptoms caused by hallucinogen use. Use it when the record documents both dependence and a hallucinogen-induced anxiety disorder.
Clinical signs
Clinical features vary; refer to documentation. Anxiety may appear with panic, excessive worry, agitation, or fear that is temporally linked to hallucinogen use.
When to use this code
Use this code when the clinician documents hallucinogen dependence and specifically links the anxiety disorder to hallucinogen use. It is appropriate for encounters where both conditions are confirmed in the chart. If the record only says anxiety or substance use without that linkage, check documentation.
Do not use for
Do not use this code for uncomplicated hallucinogen use, dependence without anxiety, or anxiety disorder unrelated to hallucinogen use. Check documentation when the substance relationship is unclear.
Coding tip
Code only when the provider explicitly connects the anxiety disorder to hallucinogen dependence.