ICD-10 Code E71.528 – Other X-linked adrenoleukodystrophy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E71.528 – Other X-linked adrenoleukodystrophy
What it is
E71.528 identifies other forms of X-linked adrenoleukodystrophy, a rare inherited disorder affecting very long-chain fatty acid metabolism. It is used when documentation specifies this X-linked subtype rather than a more general leukodystrophy.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include progressive neurologic impairment, adrenal involvement, and white matter disease on imaging in affected patients.
When to use this code
Use this code when the provider documents other X-linked adrenoleukodystrophy or an X-linked ALD variant that does not fit a more specific code. It may also apply when the record confirms the diagnosis through genetics, imaging, or specialist assessment. Check documentation if the note only says “adrenoleukodystrophy.”
Do not use for
Do not use this code for nonspecific leukodystrophy, adrenal insufficiency alone, or unrelated metabolic disorders. If the chart does not confirm an X-linked form, check documentation.
Coding tip
Verify the exact subtype in the assessment, because “adrenoleukodystrophy” without X-linked wording may require a different code.