ICD-10 Code A52.15 – Late syphilitic neuropathy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A52.15 – Late syphilitic neuropathy
What it is
A52.15 identifies late-stage syphilis affecting the nervous system, specifically neuropathy caused by longstanding infection. Use this code when documentation links nerve damage to late syphilis.
Clinical signs
Clinical features vary; refer to documentation. Reported findings may include peripheral nerve pain, sensory loss, weakness, or other neurologic deficits consistent with syphilitic nerve involvement.
When to use this code
Use A52.15 when the provider documents late syphilitic neuropathy, neurosyphilis with neuropathic involvement, or nerve damage attributed to late syphilis. It may appear in chronic neurologic presentations where the infectious cause is established. Check documentation if the record only says “neuropathy” without a syphilis link.
Do not use for
Do not use this code for neuropathy from diabetes, alcohol, trauma, or other non-syphilitic causes. If the chart does not clearly connect the neuropathy to late syphilis, code the documented condition instead.
Coding tip
Always verify that the record supports both late syphilis and neuropathy before assigning A52.15.