ICD-10 Code A52 – Late syphilis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A52 – Late syphilis
What it is
A52 identifies late-stage syphilis, an infection caused by Treponema pallidum with manifestations appearing long after the initial exposure. Use it when documentation specifies late syphilis or a late syphilitic condition.
Clinical signs
Clinical features vary; refer to documentation. Late syphilis may involve neurologic, cardiovascular, or other tertiary manifestations, and findings are often chronic rather than acute.
When to use this code
Use A52 when the record clearly states late syphilis, tertiary syphilis, or a late syphilitic manifestation without a more specific subcode. It may apply when the provider documents late disease after prior infection. If the note names a specific organ system or form, code that more detailed diagnosis instead.
Do not use for
Do not use A52 for primary, secondary, early latent, or unspecified syphilis. Also avoid it when the chart only says “history of syphilis” or the stage is not documented; check documentation.
Coding tip
Look for the word “late” in the diagnosis and code the most specific syphilis stage documented.