ICD-10 Code A52.14 – Late syphilitic encephalitis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Late syphilitic encephalitis is A52.14.
2026 ICD-10-CM Diagnosis Code A52.14 – Late syphilitic encephalitis

What it is

This code identifies encephalitis caused by late-stage syphilis, meaning inflammation of the brain due to Treponema pallidum infection. Use it when the record documents a late syphilitic neurologic process affecting the brain.

Clinical signs

Clinical features vary; refer to documentation. Reported findings may include cognitive decline, personality change, confusion, seizures, or focal neurologic deficits, depending on the extent of central nervous system involvement.

When to use this code

Use A52.14 when the provider documents late syphilitic encephalitis, neurosyphilis with encephalitic involvement, or a confirmed late syphilitic brain infection. Apply the code only when the diagnosis is clearly stated in the chart. If the note is nonspecific, check documentation before assigning the code.

Do not use for

Do not use this code for early syphilis, meningitis without encephalitis, or neurologic symptoms without documented syphilitic cause. Check documentation if the record only says “neurosyphilis” without specifying encephalitis.

Coding tip

Code the condition as documented and confirm that “late syphilitic encephalitis” or equivalent wording appears in the provider record.

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