ICD-10 Code E16.3 – Increased secretion of glucagon (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E16.3 – Increased secretion of glucagon
What it is
E16.3 identifies increased glucagon secretion, a disorder of hormone overproduction from the pancreas. It is used when documentation states excess glucagon or glucagon hypersecretion.
Clinical signs
Clinical features vary; refer to documentation. Reported findings may include symptoms of hormone excess, but the diagnosis should be based on a documented increase in glucagon secretion rather than assumed symptoms alone.
When to use this code
Use E16.3 when the provider documents increased glucagon secretion, glucagon hypersecretion, or a glucagon-secreting endocrine disorder. It may apply when the condition is confirmed clinically or by diagnostic workup and clearly identified in the record. If the note only mentions suspected disease, check documentation.
Do not use for
Do not use this code for diabetes, hypoglycemia, or other pancreatic hormone disorders unless increased glucagon secretion is specifically documented. If the record describes a tumor or syndrome without stating glucagon excess, code the documented condition instead.
Coding tip
Assign E16.3 only when the provider explicitly links the diagnosis to increased glucagon secretion; otherwise, verify the exact endocrine condition.