ICD-10 Code E16.0 – Drug-induced hypoglycemia without coma (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E16.0 – Drug-induced hypoglycemia without coma
What it is
This code identifies low blood glucose caused by a medication or other drug, without loss of consciousness. Use it when the record clearly links hypoglycemia to a drug effect.
Clinical signs
Typical findings include sweating, shakiness, hunger, confusion, or weakness. Clinical features vary; refer to documentation, and confirm that the episode is documented as drug-induced and not associated with coma.
When to use this code
Use E16.0 when the provider documents hypoglycemia as caused by insulin, oral hypoglycemics, or another drug, and the patient does not have coma. Code it for encounters focused on the adverse effect, whether the event is current or being evaluated.
If the note only says “low blood sugar” without a drug cause, check documentation. Also verify whether the record describes coma, because that would require a different code.
Do not use for
Do not use this code for hypoglycemia from non-drug causes, such as fasting or endocrine disease. Do not use it when coma is documented; check documentation for the correct code.
Coding tip
Link the hypoglycemia to the responsible drug in the record, and code the adverse effect as documented.