ICD-10 Code D55.0 – Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D55.0 – Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
What it is
This code identifies anemia caused by inherited G6PD deficiency. It means red blood cells break down too easily, leading to hemolytic anemia, often after a trigger such as certain medicines, foods, or infections.
Clinical signs
Clinical features vary; refer to documentation. Common findings include pallor, fatigue, jaundice, dark urine, and evidence of hemolysis. The record should support G6PD deficiency as the cause of the anemia.
When to use this code
Use D55.0 when the provider documents anemia due to G6PD deficiency, including hemolytic anemia attributed to this enzyme defect. Use it when the condition is confirmed or clearly stated in the assessment. If the note only says “G6PD deficiency” without anemia, check documentation.
Do not use for
Do not use this code for G6PD deficiency without anemia, or for anemia from another confirmed cause. If the anemia is unspecified or the relationship is not documented, check documentation before coding.
Coding tip
Assign D55.0 only when the provider links anemia to G6PD deficiency in the record.