ICD-10 Code C88.0 – Waldenström macroglobulinemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C88.0 – Waldenström macroglobulinemia
What it is
C88.0 identifies Waldenström macroglobulinemia, a rare type of lymphoplasmacytic lymphoma. It is used when documentation describes this specific monoclonal gammopathy with marrow involvement.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include hyperviscosity symptoms, anemia, lymphadenopathy, hepatosplenomegaly, or peripheral neuropathy.
When to use this code
Use C88.0 when the provider documents Waldenström macroglobulinemia, lymphoplasmacytic lymphoma, or an equivalent confirmed diagnosis. Code it from pathology, hematology, or oncology notes when the condition is established. Check documentation if the record only mentions IgM monoclonal gammopathy without a definitive diagnosis.
Do not use for
Do not use this code for nonspecific monoclonal gammopathy, multiple myeloma, or other lymphomas unless Waldenström macroglobulinemia is specifically documented. If the diagnosis is uncertain, check documentation.
Coding tip
Assign C88.0 only when the clinician clearly names the disorder; do not infer it from lab findings alone.