ICD-10 Code K72.01 – Acute and subacute hepatic failure with coma (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Acute and subacute hepatic failure with coma is K72.01.
2026 ICD-10-CM Diagnosis Code K72.01 – Acute and subacute hepatic failure with coma

What it is

K72.01 identifies acute or subacute liver failure accompanied by coma. Use it when documentation shows severe, rapidly developing hepatic dysfunction with impaired consciousness due to liver failure.

Clinical signs

Typical findings include altered mental status, confusion, somnolence, or unresponsiveness in the setting of acute hepatic failure. Clinical features vary; refer to documentation.

When to use this code

Use K72.01 when the provider clearly documents acute or subacute hepatic failure and coma, including hepatic encephalopathy progressing to coma. It is appropriate for inpatient or emergency records where the coma is attributed to liver failure. Check documentation if the chart only states liver failure without coma.

Do not use for

Do not use this code for chronic liver failure, unspecified hepatic failure, or coma from another cause. If coma is present but not linked to acute or subacute hepatic failure, choose the documented condition instead.

Coding tip

Confirm both the acuity and the coma in the provider note before assigning K72.01.

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