ICD-10 Code K72.00 – Acute and subacute hepatic failure without coma (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Acute and subacute hepatic failure without coma is K72.00.
2026 ICD-10-CM Diagnosis Code K72.00 – Acute and subacute hepatic failure without coma

What it is

This code identifies acute or subacute liver failure when the patient is not in coma. It describes sudden severe loss of liver function, usually requiring urgent evaluation and close monitoring.

Clinical signs

Clinical features vary; refer to documentation. Common findings include jaundice, confusion or altered mental status short of coma, coagulopathy, and evidence of rapid liver dysfunction.

When to use this code

Use K72.00 when the record clearly documents acute or subacute hepatic failure without coma. It fits cases where liver failure is present, but coma is not documented. Code the condition based on the provider’s final diagnosis, not on isolated abnormal liver tests alone.

Do not use for

Do not use this code for hepatic coma, chronic liver failure, or uncomplicated hepatitis. If the documentation is unclear about acuity or coma status, check documentation.

Coding tip

Confirm that the provider explicitly states “without coma” before assigning K72.00.

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