ICD-10 Code J45.50 – Severe persistent asthma, uncomplicated (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Severe persistent asthma, uncomplicated is J45.50.
2026 ICD-10-CM Diagnosis Code J45.50 – Severe persistent asthma, uncomplicated

What it is

J45.50 identifies severe persistent asthma without a documented complication. Use it for chronic asthma that remains severe in pattern, but the record does not mention an acute exacerbation, status asthmaticus, or another complication.

Clinical signs

Patients may have frequent daytime symptoms, nighttime awakening, and significant activity limitation. Clinical features vary; refer to documentation for severity language and whether the asthma is currently uncomplicated.

When to use this code

Use this code when the provider documents severe persistent asthma and does not describe an acute flare or status asthmaticus. It also fits encounters focused on ongoing asthma management when no complication is stated. Check documentation if the note is unclear about current severity or complications.

Do not use for

Do not use this code if the record states acute exacerbation, status asthmaticus, or another specified complication. If the documentation is incomplete, check documentation rather than assuming the uncomplicated form.

Coding tip

Match the severity term exactly as documented and verify that “uncomplicated” is supported by the note.

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