ICD-10 Code I82.21 – Embolism and thrombosis of superior vena cava (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I82.21 – Embolism and thrombosis of superior vena cava
What it is
I82.21 identifies a blood clot or embolus in the superior vena cava, the large vein that carries blood from the upper body to the heart. Use it when documentation specifically names this vessel.
Clinical signs
Findings may include swelling of the face, neck, or upper extremities, venous distention, and symptoms of superior vena cava obstruction. Clinical features vary; refer to documentation.
When to use this code
Use this code when the record clearly documents embolism or thrombosis of the superior vena cava as the diagnosis. It may appear in acute or chronic settings, but you should code only what the provider states. If the note describes a clot in another thoracic vein, check documentation.
Do not use for
Do not use I82.21 for nonspecific venous thrombosis, pulmonary embolism, or thrombosis in a different vessel. If the superior vena cava is not explicitly documented, check documentation.
Coding tip
Verify the exact vessel named in the assessment or imaging report before assigning I82.21.