ICD-10 Code D21.0 – Benign neoplasm of connective and other soft tissue of head, face and neck (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Benign neoplasm of connective and other soft tissue of head, face and neck is D21.0.
2026 ICD-10-CM Diagnosis Code D21.0 – Benign neoplasm of connective and other soft tissue of head, face and neck

What it is

This code identifies a noncancerous growth arising from connective or other soft tissue in the head, face, or neck. It is used when the lesion is benign and the site is documented in this anatomic region.

Clinical signs

Clinical features vary; refer to documentation. These lesions may present as a localized, slow-growing mass or swelling, sometimes found on exam or imaging, with pathology confirming benign behavior.

When to use this code

Use D21.0 when the provider documents a benign soft tissue tumor in the head, face, or neck and the record supports that location. Apply it after biopsy, excision, or specialist assessment when the diagnosis is clearly benign. If the site is broader or unclear, check documentation.

Do not use for

Do not use this code for malignant neoplasms, uncertain behavior, or lesions in other body sites. If the pathology or note does not confirm benign soft tissue origin, check documentation.

Coding tip

Verify both the benign nature and the exact anatomic site before assigning D21.0.

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