ICD-10 Code I70.221 – Atherosclerosis of native arteries of extremities with rest pain, right leg (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Atherosclerosis of native arteries of extremities with rest pain, right leg is I70.221.
2026 ICD-10-CM Diagnosis Code I70.221 – Atherosclerosis of native arteries of extremities with rest pain, right leg

What it is

This code identifies atherosclerosis in the native arteries of the right leg with rest pain, meaning blood flow is reduced enough to cause pain even when the patient is not walking. It reflects peripheral arterial disease affecting the right lower extremity.

Clinical signs

Typical findings include ischemic rest pain in the right leg, often worse at night or when the limb is elevated. Clinical features vary; refer to documentation for evidence of arterial insufficiency and right-sided involvement.

When to use this code

Use I70.221 when the provider documents atherosclerosis of native arteries in the right leg and specifically states rest pain. The record should support that the disease is in the native arteries, not a bypass graft or other vessel type. If laterality or pain status is unclear, check documentation.

Do not use for

Do not use this code for atherosclerosis without rest pain, for disease in the left leg, or when the affected vessel is not a native artery. If the chart does not clearly confirm rest pain, check documentation.

Coding tip

Verify both laterality and the presence of rest pain in the provider note before assigning I70.221.

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