ICD-10 Code H21.569 – Pupillary abnormality, unspecified eye (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Pupillary abnormality, unspecified eye is H21.569.
2026 ICD-10-CM Diagnosis Code H21.569 – Pupillary abnormality, unspecified eye

What it is

This code identifies an unspecified abnormality of the pupil in one eye. Use it when the record notes a pupillary disorder but does not define the exact abnormality.

Clinical signs

Clinical features vary; refer to documentation. Findings may include an abnormal pupil shape, size, or reaction to light, but the specific pattern is not documented.

When to use this code

Use H21.569 when the clinician documents a pupillary abnormality in an unspecified eye and no more specific diagnosis is available. It may apply when the note describes anisocoria, irregular pupil response, or other pupil changes without further detail. Check documentation if laterality or cause is stated elsewhere.

Do not use for

Do not use this code if the chart identifies a specific pupillary disorder, such as a traumatic or pharmacologic cause. Also avoid it when the affected eye is documented more specifically.

Coding tip

Query for laterality and etiology when the note only says “pupillary abnormality.”

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