ICD-10 Code H21.563 – Pupillary abnormality, bilateral (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Pupillary abnormality, bilateral is H21.563.
2026 ICD-10-CM Diagnosis Code H21.563 – Pupillary abnormality, bilateral

What it is

H21.563 identifies an abnormal pupil finding affecting both eyes. Use it when documentation describes bilateral pupillary irregularity, abnormal size, shape, or reaction, without a more specific diagnosis.

Clinical signs

Clinical features vary; refer to documentation. Findings may include unequal or irregular pupils, abnormal constriction or dilation, or other bilateral pupillary changes noted on eye examination.

When to use this code

Use this code when the provider documents a bilateral pupillary abnormality and does not name a more specific underlying condition. It is appropriate for recorded exam findings in the chart, consult note, or assessment. If the abnormality is linked to another disorder, code the documented cause when instructed.

Do not use for

Do not use this code for unilateral pupillary findings or for a specific diagnosed eye disease with its own code. Check documentation if the note only describes a symptom without confirming bilateral involvement.

Coding tip

Look for explicit bilateral wording and avoid assigning H21.563 when the record supports a more specific diagnosis.

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