ICD-10 Code F55.8 – Abuse of other non-psychoactive substances (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Abuse of other non-psychoactive substances is F55.8.
2026 ICD-10-CM Diagnosis Code F55.8 – Abuse of other non-psychoactive substances

What it is

Use this code for harmful or excessive use of non-psychoactive substances, such as medications or products taken in a way that causes physical or psychological problems. It is not for alcohol, tobacco, or psychoactive drug misuse.

Clinical signs

Clinical features vary; refer to documentation. You may see repeated use despite harm, concern about the substance, or symptoms tied to overuse, but the record should support abuse rather than simple use.

When to use this code

Use F55.8 when the provider documents abuse of a non-psychoactive substance and the substance is not better classified elsewhere. This may apply when the chart identifies misuse, overuse, or dependence-like behavior involving a non-psychoactive agent. Check documentation for the exact substance and context.

Do not use for

Do not use this code for alcohol, nicotine, or psychoactive substance use disorders. Also avoid it when the record describes routine therapeutic use, poisoning, or adverse effects without abuse.

Coding tip

Verify the substance name and the provider’s wording; if the record is vague, code only what is clearly documented.

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