ICD-10 Code F11.222 – Opioid dependence with intoxication with perceptual disturbance (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Opioid dependence with intoxication with perceptual disturbance is F11.222.
2026 ICD-10-CM Diagnosis Code F11.222 – Opioid dependence with intoxication with perceptual disturbance

What it is

This code identifies opioid dependence with current intoxication and perceptual disturbance, such as hallucinations or other altered sensory experiences. Use it when the record shows both dependence and intoxication-related perceptual symptoms.

Clinical signs

Clinical features vary; refer to documentation. You may see opioid intoxication signs together with perceptual disturbance, including hallucinations or misperceptions, in a patient with documented opioid dependence.

When to use this code

Use this code when the provider documents opioid dependence and states that intoxication is accompanied by perceptual disturbance. It fits encounters where the mental status change is part of the intoxication picture, not a separate psychotic disorder. Check documentation if the record does not clearly link the perceptual symptoms to opioid intoxication.

Do not use for

Do not use this code for opioid dependence without intoxication, or for intoxication without perceptual disturbance. If the chart does not specify dependence or does not connect the hallucination-like symptoms to opioids, check documentation.

Coding tip

Confirm that the provider documents both dependence and intoxication with perceptual disturbance before assigning F11.222.

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