ICD-10 Code F06.33 – Mood disorder due to known physiological condition with manic features (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F06.33 – Mood disorder due to known physiological condition with manic features
What it is
This code identifies a mood disorder caused by a known physiological condition, with manic features present. Use it when the mood change is attributed to an underlying medical cause rather than a primary bipolar disorder.
Clinical signs
Clinical features may include elevated or irritable mood, increased energy, decreased need for sleep, pressured speech, or impulsive behavior. Clinical features vary; refer to documentation and confirm the medical condition driving the mood change.
When to use this code
Use F06.33 when the record clearly links manic symptoms to a documented physiological condition, such as a neurologic, endocrine, or other medical disorder. You should code the underlying condition as well, when documented. If the cause is not established, check documentation before assigning this code.
Do not use for
Do not use this code for primary bipolar disorder or isolated manic episodes without a confirmed physiological cause. Check documentation if the chart only states mood changes, agitation, or behavioral disturbance.
Coding tip
Verify that the provider documents both the physiological condition and the manic features, because F06.33 depends on that causal connection.