ICD-10 Code F06.32 – Mood disorder due to known physiological condition with major depressive-like episode (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Mood disorder due to known physiological condition with major depressive-like episode is F06.32.
2026 ICD-10-CM Diagnosis Code F06.32 – Mood disorder due to known physiological condition with major depressive-like episode

What it is

This code identifies a depressive syndrome caused by a known medical condition. Use it when the mood change is directly linked to the physiological condition, not a primary depressive disorder.

Clinical signs

Typical findings include persistent depressed mood, loss of interest, low energy, and other depressive symptoms tied to the underlying condition. Clinical features vary; refer to documentation.

When to use this code

Use F06.32 when the record states that a medical illness is causing a major depressive-like episode. The documentation should connect the mood symptoms to the physiological condition. Choose this code when the depressive presentation is clinically significant and not better explained by a primary mood disorder.

Do not use for

Do not use it for uncomplicated sadness, adjustment reactions, or depression without a documented medical cause. If the chart does not support the causal link, check documentation.

Coding tip

Confirm both the underlying condition and the provider’s explicit attribution of the depressive episode before assigning F06.32.

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