ICD-10 Code E88.09 – Other disorders of plasma-protein metabolism, not elsewhere classified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E88.09 – Other disorders of plasma-protein metabolism, not elsewhere classified
What it is
This code identifies disorders affecting plasma proteins, such as abnormal protein levels or protein handling, when the condition does not fit a more specific diagnosis. Use it for documented plasma-protein metabolism problems that are otherwise unspecified.
Clinical signs
Clinical features vary; refer to documentation. Findings may include abnormal serum protein results, edema, weakness, or signs tied to the underlying disorder causing protein imbalance.
When to use this code
Use E88.09 when the provider documents a disorder of plasma-protein metabolism without naming a more specific condition. It may also apply when the record describes abnormal plasma proteins, but the exact diagnosis remains unclear. Code the documented disorder, not the lab result alone.
Do not use for
Do not use this code for isolated abnormal laboratory findings without a diagnosed disorder. Do not use it when a more specific metabolic, renal, hepatic, or protein-related diagnosis is documented.
Coding tip
Review the assessment and problem list carefully; if the provider names a specific cause, code that condition instead of E88.09.